diff --git a/Cargo.toml b/Cargo.toml
index 7c4aba1..de45d4d 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -130,12 +130,14 @@ opentelemetry = { version = "0.31", default-features = false, features = ["trace
 opentelemetry_sdk = { version = "0.31", default-features = false, features = ["trace", "metrics"] }
 opentelemetry-otlp = { version = "0.31", default-features = false, features = ["trace", "metrics", "http-proto", "reqwest-client", "reqwest-rustls-webpki-roots"] }
 
-# USB device enumeration (hardware discovery)
-nusb = { version = "0.2", default-features = false, optional = true }
-
 # Serial port for peripheral communication (STM32, etc.)
 tokio-serial = { version = "5", default-features = false, optional = true }
 
+# USB device enumeration (hardware discovery) — only on platforms nusb supports
+# (Linux, macOS, Windows). Android/Termux uses target_os="android" and is excluded.
+[target.'cfg(any(target_os = "linux", target_os = "macos", target_os = "windows"))'.dependencies]
+nusb = { version = "0.2", default-features = false, optional = true }
+
 # probe-rs for STM32/Nucleo memory read (Phase B)
 probe-rs = { version = "0.30", optional = true }
 
diff --git a/src/hardware/discover.rs b/src/hardware/discover.rs
index 4bbf31f..9f514da 100644
--- a/src/hardware/discover.rs
+++ b/src/hardware/discover.rs
@@ -1,4 +1,10 @@
 //! USB device discovery — enumerate devices and enrich with board registry.
+//!
+//! USB enumeration via `nusb` is only supported on Linux, macOS, and Windows.
+//! On Android (Termux) and other unsupported platforms this module is excluded
+//! from compilation; callers in `hardware/mod.rs` fall back to an empty result.
+
+#![cfg(any(target_os = "linux", target_os = "macos", target_os = "windows"))]
 
 use super::registry;
 use anyhow::Result;
diff --git a/src/hardware/mod.rs b/src/hardware/mod.rs
index 18f6dcc..d9dbc1c 100644
--- a/src/hardware/mod.rs
+++ b/src/hardware/mod.rs
@@ -4,10 +4,10 @@
 
 pub mod registry;
 
-#[cfg(feature = "hardware")]
+#[cfg(all(feature = "hardware", any(target_os = "linux", target_os = "macos", target_os = "windows")))]
 pub mod discover;
 
-#[cfg(feature = "hardware")]
+#[cfg(all(feature = "hardware", any(target_os = "linux", target_os = "macos", target_os = "windows")))]
 pub mod introspect;
 
 use crate::config::Config;
@@ -28,8 +28,9 @@ pub struct DiscoveredDevice {
 /// Auto-discover connected hardware devices.
 /// Returns an empty vec on platforms without hardware support.
 pub fn discover_hardware() -> Vec<DiscoveredDevice> {
-    // USB/serial discovery is behind the "hardware" feature gate.
-    #[cfg(feature = "hardware")]
+    // USB/serial discovery is behind the "hardware" feature gate and only
+    // available on platforms where nusb supports device enumeration.
+    #[cfg(all(feature = "hardware", any(target_os = "linux", target_os = "macos", target_os = "windows")))]
     {
         if let Ok(devices) = discover::list_usb_devices() {
             return devices
@@ -102,7 +103,15 @@ pub fn handle_command(cmd: crate::HardwareCommands, _config: &Config) -> Result<
         return Ok(());
     }
 
-    #[cfg(feature = "hardware")]
+    #[cfg(all(feature = "hardware", not(any(target_os = "linux", target_os = "macos", target_os = "windows"))))]
+    {
+        let _ = &cmd;
+        println!("Hardware USB discovery is not supported on this platform.");
+        println!("Supported platforms: Linux, macOS, Windows.");
+        return Ok(());
+    }
+
+    #[cfg(all(feature = "hardware", any(target_os = "linux", target_os = "macos", target_os = "windows")))]
     match cmd {
         crate::HardwareCommands::Discover => run_discover(),
         crate::HardwareCommands::Introspect { path } => run_introspect(&path),
@@ -110,7 +119,7 @@ pub fn handle_command(cmd: crate::HardwareCommands, _config: &Config) -> Result<
     }
 }
 
-#[cfg(feature = "hardware")]
+#[cfg(all(feature = "hardware", any(target_os = "linux", target_os = "macos", target_os = "windows")))]
 fn run_discover() -> Result<()> {
     let devices = discover::list_usb_devices()?;
 
@@ -138,7 +147,7 @@ fn run_discover() -> Result<()> {
     Ok(())
 }
 
-#[cfg(feature = "hardware")]
+#[cfg(all(feature = "hardware", any(target_os = "linux", target_os = "macos", target_os = "windows")))]
 fn run_introspect(path: &str) -> Result<()> {
     let result = introspect::introspect_device(path)?;
 
@@ -160,7 +169,7 @@ fn run_introspect(path: &str) -> Result<()> {
     Ok(())
 }
 
-#[cfg(feature = "hardware")]
+#[cfg(all(feature = "hardware", any(target_os = "linux", target_os = "macos", target_os = "windows")))]
 fn run_info(chip: &str) -> Result<()> {
     #[cfg(feature = "probe")]
     {
@@ -192,7 +201,7 @@ fn run_info(chip: &str) -> Result<()> {
     }
 }
 
-#[cfg(all(feature = "hardware", feature = "probe"))]
+#[cfg(all(feature = "hardware", feature = "probe", any(target_os = "linux", target_os = "macos", target_os = "windows")))]
 fn info_via_probe(chip: &str) -> anyhow::Result<()> {
     use probe_rs::config::MemoryRegion;
     use probe_rs::{Session, SessionConfig};